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Dcasd libid(sx div); dcasd amount smn lasd duing sx; impotnc (toubl gtting kping an ction); bast tndnss nlagmnt.

Inom mn tatd with AVODAT that thy should not donat blood until at last 6 months ollowing thi last dos tpvnt pgnant womn om civing dutastid though blood tansusion [s WANINGS AND PCAUTIONS ]. Sum lvls dutastid a dtctabl 4 t6 months at tatmnt nds [s CLINICAL PHAMACOLOGY ].

In an oal p- and post-natal dvlopmnt study in ats, dutastid doss 0.05, 2.5, 12.5, 30 mg/kg/day w administd. Unquivocal vidnc minization th gnitalia (i.., dcasd anognital distanc, incasd incidnc hypospadias, nippl dvlopmnt) mal osping occud at 14- t90-old th MHD (animal doss 2.5 mg/kg/day gat). At 0.05-old th xpctd clinical xposu (animal dos 0.05 mg/kg/day), vidnc minization was limitd ta small, but statistically signiicant, dcas in anognital distanc. Animal doss 2.5 t30 mg/kg/day sultd in polongd gstation in th pantal mals and a dcas in tim tvaginal patncy mal osping and a dcas in postat and sminal vsicl wights in mal osping. cts on nwbon statl spons w notd at doss gat than qual t12.5 mg/kg/day. Incasd stillbiths w notd at 30 mg/kg/day.

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