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In generalthe recommended duration of therapy for candidemia is for 2 weeks after first negative blood culture result and resolution of signs and symptoms attributable to candidemia.
ZidovudineFluconazole increases C max and AUC of zidovudine by 84and 74respectivelydue to an approx45decrease in oral zidovudine clearanceThe half-life of zidovudine was likewise prolonged by approximately 128following combination therapy with fluconazolePatients receiving this combination should be monitored for the development of zidovudine-related adverse reactionsDose reduction of zidovudine may be considered.
LosartanFluconazole inhibits the metabolism of losartan to its active metaboliteE-31 74which is responsible for most of the angiotensin II-receptor antagonism which occurs during treatment with losartanPatients should have their blood pressure monitored continuously.
The liquid form of Diflucan contains sucroseTalk to your doctor before using this form of fluconazole if you have a problem digesting sugars or milk.
During pregnancythis medication should be used only when clearly neededIt may harm an unborn baby if taken during the first 3 months of pregnancyAsk about reliable forms of birth control while using this medication and for 1 week after stopping treatmentFor the treatment of vaginal yeast infectionsmedications applied in or around the vagina should be considered before this medicationDiscuss the risks and benefits with your doctor.
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