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Seek emergency medical attention or call the Poison Help line at 1-800-222-1222A glipizide overdose can cause life-threatening hypoglycemia.

This is not a complete list of side effects and others may occurCall your doctor for medical advice about side effectsYou may report side effects to FDA at 1-800-FDA-1088.

Symptoms of severe hypoglycemia include extreme weaknessblurred visionsweatingtrouble speakingtremorsstomach painconfusionand seizureconvulsions

What other drugs will affect glipizideGlipiZIDE XLGlucotrolGlucotrol XL

The hypoglycemic action of sulfonylureas may be potentiated by certain drugs including nonsteroidal anti-inflammatory agentssome azolesand other drugs that are highly protein boundsalicylatessulfonamideschloramphenicolprobenecidcoumarinsmonoamine oxidase inhibitorsquinolones and beta adrenergic blocking agentsconverselycertain drugs tend to produce hyperglycemia and may lead to loss of controlincluding thiazides and other diureticscorticosteroidsphenothiazinesthyroid productsestrogensoral contraceptivesphenytoinnicotinic acidsympathomimeticscalcium channel blocking drugsand isoniazidwhen coadministering glipizide with such drugspatient should be observed closely for hypoglycemia or hyperglycemiawhen such drugs are withdrawnobserve patient closely for loss of control.

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