Events observed during the pre-marketing evaluation of lioresal intrathecal.

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Because of the possibility of sedationpatients should be cautioned regarding the operation of automobiles or other dangerous machineryand activities made hazardous by decreased alertnessPatients should also be cautioned that the central nervous system effects of Lioresal may be additive to those of alcohol and other CNS depressants.

Special attention must be given to recognizing the signs and symptoms of overdosageespecially during the initial screening and dose-titration phase of treatmentbut also during re-introduction of LIORESAL INTRATHECAL after a period of interruption in therapy.

This is not a complete list of possible side effectsIf you notice other effects not listed abovecontact your doctor or pharmacist.

MusculoskeletalThe onset of scoliosis or worsening of a pre-existing scoliosis has been reportedUrogenitalSexual dysfunction in men and womenincluding decreased libido and orgasm dysfunctionhave been reportedErectile dysfunction in men has also been reportedPriapism has been reported following baclofen withdrawal.

During pregnancythis medication should be used only when clearly neededDiscuss the risks and benefits with your doctor.

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