Nsaids, including ponstel, should be used with caution in patients with hypertension.

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Taking an NSAID can increase your risk of life-threatening heart or circulation problemsincluding heart attack or strokeThis risk will increase the longer you use an NSAIDDo not use this medicine just before or after having heart bypass surgeryalso called coronary artery bypass graftor CABG

Ponstel has not been adequately investigated in pediatric patients less than 14 years of ageA study in 17 preterm infants administered 2 mg/kg indicated that the half-life was about five times as long as adultsconsistent with the low activity of metabolic enzymes in newborn infantsThe mean C max in this study was 4 mcg/mLrange 2.9-6.1The mean time to maximum concentrationT maxwas 8 hoursrange 2-18 hours

Signs of an allergic reactionlike rashhivesitchingredswollenblisteredor peeling skin with or without feverwheezingtightness in the chest or throattrouble breathingswallowingor talkingunusual hoarsenessor swelling of the mouthfacelipstongueor throatSigns of bleeding like throwing up blood or throw up that looks like coffee groundscoughing up bloodblood in the urineblackredor tarry stoolsbleeding from the gumsvaginal bleeding that is not normalbruises without a reason or that get biggeror any bleeding that is very bad or that you cannot stopSigns of kidney problems like unable to pass urinechange in how much urine is passedblood in the urineor a big weight gainSigns of high potassium levels like a heartbeat that does not feel normalfeeling confusedfeeling weaklightheadedor dizzyfeeling like passing outnumbness or tinglingor shortness of breathSigns of high blood pressure like very bad headache or dizzinesspassing outor change in eyesightShortness of breatha big weight gainor swelling in the arms or legsChest pain or pressure or a fast heartbeatWeakness on 1 side of the bodytrouble speaking or thinkingchange in balancedrooping on one side of the faceor blurred eyesightFeeling very tired or weakRinging in earsMood changesLow mooddepressionVery bad belly painVery bad back painA very bad skin reactionStevens-Johnson syndrome/toxic epidermal necrolysismay happenIt can cause very bad health problems that may not go awayand sometimes deathGet medical help right away if you have signs like redswollenblisteredor peeling skinwith or without feverred or irritated eyesor sores in your mouththroatnoseor eyes.

If you take mefenamic acid for a long period of timeyour doctor may want to check you on a regular basis to make sure this medication is not causing harmful effectsDo not miss any scheduled visits to your doctor.

Mefenamic acid is used to treat pain or inflammation caused by arthritisIt is also used to treat menstrual pain.

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