Nexium relieves heartburn and other symptoms caused by the backflow of stomach acid into the canal to the stomach the esophagus a condition known as gastroesophageal reflux disease.

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Nexium is used to treat symptoms of gastroesophageal reflux diseaseGERDand other conditions involving excessive stomach acid such as Zollinger-Ellison syndromeIt is also used to promote healing of erosive esophagitisdamage to your esophagus caused by stomach acid

This medicine is usually given for 4 to 8 weeks onlyYour doctor may recommend a second course of treatment if you need additional healing time.

A single oral dose of esomeprazole at 510 mg/kgabout 124 times the human dose on a body surface area basiswas lethal to ratsThe major signs of acute toxicity were reduced motor activitychanges in respiratory frequencytremorataxiaand intermittent clonic convulsions.

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