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Mebeverine violates the entrance of Naions into the cell by preventing the fast sodium channels myocyte cell membranealso it blocks the entering through the slow channels of ions Ca2hinders the process of depolarization of the cell membrane and prevents the reduction of muscle fibersMebeverine does not have an anticholinergic actionIt directly relaxes smooth musclemainly in the gastrointestinal tractThe preparation eliminates spasmwithout exerting a significant effect on the normal intestinal peristalsis.

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Colofac is taken orally 20 minutes before a meal without chewing and drinking waterExaminees older than 12 years should the preparation 2 times daily200 mgThe capsule must be swallowed without chewingand drank with waterThe duration of curing is determined by the physician individually.

Colospa 135Mg Tablet helps treat symptoms of intestinal disorders and irritable bowel problemssuch as spastic colitisspastic constipationcolon irritation and mucous colitisThe drug belong to the group of medicines called anti-spasmodicsIt helps relax intestinal muscleswhich in turn reduces pain and irritability.

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