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That said, a blood sample will be highly accurate in determining the amount of promethazine present within plasma.

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Promethazine may cause breathing to slow or stopand may cause death in childrenPromethazine should not be given to babies or children who are younger than 2 years old and should be given with caution to children who are 2 years of age or olderCombination products containing promethazine and codeine should not be given to children younger than 16 years oldPromethazine should not routinely be used to treat vomiting in childrenit should only be used in specific cases when a doctor decides that it is neededTell your child’s doctor if your child has any condition that affects his/her breathing such as lung diseaseasthmaor sleep apneastops breathing for short periods of time during sleepTell your doctor or pharmacist about all the medications your child is takingespecially barbiturates such as phenobarbitalLuminalmedications for anxietynarcotic medications for painsedativessleeping pillsand tranquilizersCall your child’s doctor immediately and get emergency medical treatment if your child has difficulty breathingwheezesslows or pauses in breathingor stops breathing.

Promethazine hydrochloride in 12.5to 25-mg doses for children and 50-mg doses for adults the night before surgery relieves apprehension and produces a quiet sleep.

Cold or allergy medicinesedativesnarcotic pain medicinesleeping pillsmuscle relaxersand medicine for seizuresdepression or anxiety can interact with promethazine and cause medical problems or increase side effectsTell your doctor if you regularly use any of these medicines.

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