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PLAQUENIL is not effective against chloroquine-resistant strains of Pfalciparum.

Retinal toxicity is largely dose-relatedThe risk of retinal damages is small with daily doses of up to 6.5 mg/kg body weightExceeding the recommended daily dose sharply increases the risk of retinal toxicityThis examination should be more frequent and adapted to the patient in the following situations:

In adults400 mg310 mg baseon exactly the same day of each weekIn infants and childrenthe weekly suppressive dosage is 5 mgcalculated as baseper kg of body weightbut should not exceed the adult dose regardless of weight.

Blurred visionWhile taking this medicationuse caution when driving or operating machinerysince hydroxychloroquine can cause blurring of visionIf your vision blurscall your doctor.

Irreversible retinal damage has been observed in some patients who had received long-term or highdosage 4-aminoquinoline therapy for discoid and systemic lupus erythematosusor rheumatoid arthritis.

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