If you or a loved one has developed tardive dyskinesia after taking reglan, you need to act quickly.

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The diagnostic evaluation of patients with this syndrome is complicatedIn arriving at a diagnosisit is important to identify cases where the clinical presentation includes both serious medical illnesse.gpneumoniasystemic infectionetcand untreated or inadequately treated extrapyramidal signs and symptomsEPSOther important considerations in the differential diagnosis include central anticholinergic toxicityheat strokemalignant hyperthermiadrug fever and primary central nervous systemCNSpathology.

Treatment with metoclopramide can cause tardive dyskinesiaTDa potentially irreversible and disfiguring disorder characterized by involuntary movements of the facetongueor extremitiesThe risk of developing tardive dyskinesia increases with the duration of treatment and the total cumulative doseAn analysis of utilization patterns showed that about 20of patients who used metoclopramide took it for longer than 12 weeksTreatment with metoclopramide for longer than the recommended 12 weeks should be avoided in all but rare cases where therapeutic benefit is thought to outweigh the risk of developing TD.

Safety and effectiveness in pediatric patients have not been established except as stated to facilitate small bowel intubationsee OVERDOSAGE and DOSAGE AND ADMINISTRATION

Intravenous injections of undiluted metoclopramide should be made slowly allowing 1 to 2 minutes for 10 mg since a transient but intense feeling of anxiety and restlessnessfollowed by drowsinessmay occur with rapid administration.

Intravenous injections of undiluted metoclopramide should be made slowly allowing 1 to 2 minutes for 10 mg since a transient but intense feeling of anxiety and restlessnessfollowed by drowsinessmay occur with rapid administration.

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