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Avoid getting up too fast from a sitting or lying positionor you may feel dizzyGet up slowly and steady yourself to prevent a fall.

Amlodipine is a weak inhibitor of CYP3A and may increase exposure to CYP3A substrates.

Some antihypertensive drugs have smaller blood pressure effectsas monotherapyin black patientsand many antihypertensive drugs have additional approved indications and effectse.gon anginaheart failureor diabetic kidney diseaseThese considerations may guide selection of therapy.

Tell your doctor right away if any of these unlikely but serious side effects occurfast/irregular/pounding heartbeatfainting.

As with other calcium channel blockershemodynamic measurements of cardiac function at rest and during exerciseor pacingin patients with normal ventricular function treated with Norvasc have generally demonstrated a small increase in cardiac index without significant influence on dP/dt or on left ventricular end diastolic pressure or volumeIn hemodynamic studiesNorvasc has not been associated with a negative inotropic effect when administered in the therapeutic dose range to intact animals and maneven when co-administered with beta-blockers to manSimilar findingshoweverhave been observed in normal or well-compensated patients with heart failure with agents possessing significant negative inotropic effects.

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