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See ContraindicationsMay cause hypotension or increased BUN with diureticsMay cause hyperkalemia with Ksparing diureticsKsupplementsor Kcontaining salt substitutesRisk of hypoglycemia with concomitant antidiabetic agentsadjust dosesMay be antagonized byand renal toxicity potentiated by NSAIDsincluding COX-2 inhibitorsmonitor renal function in elderly and/or volume-depletedDual inhibition of the renin-angiotensin system with ARBsACEIsor aliskiren may increase risk of hypotensionhyperkalemiarenal function changesmonitor closelyConcomitant aliskiren in diabetics or renal impairmentGFR.

Take the missed dose as soon as you rememberSkip the missed dose if it is almost time for your next scheduled doseDo not take extra medicine to make up the missed dose.

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