Contraindications to bupropion include a history of seizures, an eating disorder, and monoamine oxidase inhibitor use within 2 wk.

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Aplenzinbupropion hydrobromide174 mg PO qDay initiallyequivalent to 150 mg bupropion HClafter 1 weekmay increase to usual target dose of 348 mg/dayequivalent to 300 mg bupropion HCL)

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