Moreover to avoid any risk factor the physicians generally start the medication at a low dose which is 5mg lioresal is taken with or without the food.

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Spasticity of Spinal Cord OriginEvidence supporting the efficacy of LIORESAL INTRATHECAL was obtained in randomizedcontrolled investigations that compared the effects of either a single intrathecal dose or a three day intrathecal infusion of LIORESAL INTRATHECAL to placebo in patients with severe spasticity and spasms due to either spinal cord trauma or multiple sclerosisLIORESAL INTRATHECAL was superior to placebo on both principal outcome measures employedchange from baseline in the Ashworth rating of spasticity and the frequency of spasms.

As a groupthe patients who died were relatively youngmean age was 47 with a range from 25 to 63but the majority suffered from severe spasticity of many years durationwere nonambulatoryhad various medical complications such as pneumoniaurinary tract infectionsand decubitiand/or had received multiple concomitant medicationsA case-by-case review of the clinical course of the 16 patients who died failed to reveal any unique signssymptomsor laboratory results that would suggest that treatment with LIORESAL INTRATHECAL caused their deathsTwo patientshoweverdid suffer sudden and unexpected death within 2 weeks of pump implantation and one patient died unexpectedly after screening.

Before using this medicationtell your doctor or pharmacist your medical historyespecially ofkidney diseasemental/mood disorderssuch as schizophreniabrain disorderssuch as seizuresstroke

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